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An alcohol substitute that mimics its pleasant buzz without leading to drunkenness and hangovers is being developed by scientists.

Just because it sounds too good to be true doesn't necessarily mean it isn't. That being said, I don't think I'd be first in line to try it. Maybe second, though.

Lonedar wrote:

Just because it sounds too good to be true doesn't necessarily mean it isn't. That being said, I don't think I'd be first in line to try it. Maybe second, though.

It doesn't just sound too good to be true, it sounds like a horrible, horrible idea designed at targeting a new recreational drug to individuals who don't need it. Alcohol without the side effects is, well, you guessed it, another drug. This is not modifying alcohol to moderate the side effects and toxicity, this is taking another psychoactive drug and calling it 'alcohol'.

NO!

NO!

NO!

NO!

NO!

Benzos are nasty drugs with a high addiction potential, which is worse for people who have an alcohol problem. It messes with memory and cognition. Also even if a person does not become addicted to it, it can create severe withdrawal symptoms when they STOP using it regularly.

<end rant>

Squirrel Girl wrote:

Benzo's are the generally and highly interactive with almost anything drug champion as well. Squirrel Girl is being nice about it.

Come on, man. They had it in 'Star Trek.' It's the future. What's there not to like (assuming no harmful physical side effects)?

Seriously, who wouldn't be for being able to turn a buzz on and off at will? Once again assuming they can actually make it no more physically harmful than alcohol already is.

Author:	Shelgeyr [ Mon Feb 08, 2010 12:28 pm ]
Post subject:	Synthehol?
The Telegraph wrote: An alcohol substitute that mimics its pleasant buzz without leading to drunkenness and hangovers is being developed by scientists. Rest of article at link.

Author:	NephyrS [ Mon Feb 08, 2010 12:33 pm ]
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Benzo's are not a drug I would take recreationally, but that's just me.

Author:	Rafael [ Mon Feb 08, 2010 12:33 pm ]
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Do not want!

Author:	Lonedar [ Mon Feb 08, 2010 12:40 pm ]
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I'm intrigued. If this puts the two martini lunch back on the menu, then I'm for it. Better life through chemistry!

Author:	NephyrS [ Mon Feb 08, 2010 12:49 pm ]
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Just went and did a quick runthrough of a review article of benzo type drugs metabolism, and I'm not seeing any derivatives opening up for non-prescription use any time soon. Several have carcinogenic metabolites, others have very, very bad interactions with other dugs, and all have very bad side effects from overdoses. If interested and you have access somehow, the paper was Benzodiazepine Metabolism: An Analytical Perspective, from the journal of Current Drug Metabolism.

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Author:	Squirrel Girl [ Mon Feb 08, 2010 1:55 pm ]
Post subject:	Re: Synthehol?
NO! NO! NO! NO! NO! Benzos are nasty drugs with a high addiction potential, which is worse for people who have an alcohol problem. It messes with memory and cognition. Also even if a person does not become addicted to it, it can create severe withdrawal symptoms when they STOP using it regularly. <end rant>

Author:	Müs [ Mon Feb 08, 2010 2:00 pm ]
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[youtube]DrzkKjOu79k[/youtube]

Author:	Aizle [ Mon Feb 08, 2010 2:06 pm ]
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yeah, that just seems like a bad idea.

Author:	Loki [ Mon Feb 08, 2010 2:11 pm ]
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My Biochemistry senses tell me this is a bad idea.

Author:	Lonedar [ Mon Feb 08, 2010 2:17 pm ]
Post subject:
Just because it sounds too good to be true doesn't necessarily mean it isn't. That being said, I don't think I'd be first in line to try it. Maybe second, though.

Author:	NephyrS [ Mon Feb 08, 2010 3:37 pm ]
Post subject:	Re:
Lonedar wrote: Just because it sounds too good to be true doesn't necessarily mean it isn't. That being said, I don't think I'd be first in line to try it. Maybe second, though. It doesn't just sound too good to be true, it sounds like a horrible, horrible idea designed at targeting a new recreational drug to individuals who don't need it. Alcohol without the side effects is, well, you guessed it, another drug. This is not modifying alcohol to moderate the side effects and toxicity, this is taking another psychoactive drug and calling it 'alcohol'.

Author:	Lonedar [ Mon Feb 08, 2010 5:10 pm ]
Post subject:	Re: Re:
NephyrS wrote: Lonedar wrote: Just because it sounds too good to be true doesn't necessarily mean it isn't. That being said, I don't think I'd be first in line to try it. Maybe second, though. It doesn't just sound too good to be true, it sounds like a horrible, horrible idea designed at targeting a new recreational drug to individuals who don't need it. Alcohol without the side effects is, well, you guessed it, another drug. This is not modifying alcohol to moderate the side effects and toxicity, this is taking another psychoactive drug and calling it 'alcohol'. Come on, man. They had it in 'Star Trek.' It's the future. What's there not to like (assuming no harmful physical side effects)? Seriously, who wouldn't be for being able to turn a buzz on and off at will? Once again assuming they can actually make it no more physically harmful than alcohol already is.

Author:	Micheal [ Mon Feb 08, 2010 6:17 pm ]
Post subject:	Re: Synthehol?
Squirrel Girl wrote: NO! NO! NO! NO! NO! Benzos are nasty drugs with a high addiction potential, which is worse for people who have an alcohol problem. It messes with memory and cognition. Also even if a person does not become addicted to it, it can create severe withdrawal symptoms when they STOP using it regularly. <end rant> Benzo's are the generally and highly interactive with almost anything drug champion as well. Squirrel Girl is being nice about it.

Author:	Lydiaa [ Mon Feb 08, 2010 6:20 pm ]
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How will mothers across the world do in the morning to punish their child if not for the hangovers?

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Author:	NephyrS [ Mon Feb 08, 2010 6:26 pm ]
Post subject:	Re: Synthehol?
Micheal wrote: Squirrel Girl wrote: NO! NO! NO! NO! NO! Benzos are nasty drugs with a high addiction potential, which is worse for people who have an alcohol problem. It messes with memory and cognition. Also even if a person does not become addicted to it, it can create severe withdrawal symptoms when they STOP using it regularly. <end rant> Benzo's are the generally and highly interactive with almost anything drug champion as well. Squirrel Girl is being nice about it. It depends on the benzo, but yes. Some have the fewest side interactions of almost any drug, some have a ton of side reactions- a lot of it depends on which of the cytochrome 'clusters' is primarily responsible for its metabolism. The paper I linked above also includes in depth analyses of the side interactions of a variety of common Benzo's.

Author:	Micheal [ Mon Feb 08, 2010 6:31 pm ]
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True, I was too inclusive. I've been seeing a lot of the side reactions with drugs cases in my work, especially when I worked with the methadone programs. At first I thought the methadone-benzo interaction was the big problem, then I found out how some of the benzos don't seem to be safe to take with anything besides water. Not a drug you want to open up to more people for more abuse than its already getting.

Author:	Shelgeyr [ Tue Feb 09, 2010 8:09 pm ]
Post subject:	Re: Re:
Lonedar wrote: Come on, man. They had it in 'Star Trek.' It's the future. What's there not to like (assuming no harmful physical side effects)? Seriously, who wouldn't be for being able to turn a buzz on and off at will? Once again assuming they can actually make it no more physically harmful than alcohol already is. This is pretty much where my thoughts lie. If a substance can be crafted that will produce the "light buzz" effect, without being capable of producing the "sloppy, falling down drunk" effect, and has no drug interactions or harmful side effects, I will vote it a "good thing". Is it possible? I dunno. I'm not the chemist. I just wanted to share the article.