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Life... finds a way
https://gladerebooted.net/viewtopic.php?f=5&t=7857
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Author:  Lenas [ Thu Dec 08, 2011 11:52 pm ]
Post subject:  Life... finds a way

http://news.yahoo.com/blogs/trending-no ... 55149.html

Quote:
Scientific Discovery May Lead to Woolly Mammoths Roaming Earth
...these now extinct prehistoric animals roamed the Earth more than 10,000 years ago, but they may be coming back. Scientists from Russia and Japan are working to bring woolly mammoths back by cloning the giant within the next five years. A mammoth thigh bone was found under permafrost soil in Siberia with its marrow in unusually well preserved condition. The Sakha Republic's mammoth museum and Japan's Kinki University will team up to recreate the mammoth using DNA taken from the marrow that is then put into the nuclei of egg cells of common elephants. The next step is implanting the embryos into elephant wombs to be delivered. Since the two species are close relatives, scientists are not foreseeing many complications. So what does this mean for us? There very well could be a new breed of woolly mammoth walking our planet by 2016.

Author:  Lex Luthor [ Fri Dec 09, 2011 12:47 am ]
Post subject: 

That's pretty amazing.

Author:  Müs [ Fri Dec 09, 2011 1:37 am ]
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Woohoo! Just one more step to Utahraptors!

Author:  Lex Luthor [ Fri Dec 09, 2011 1:44 am ]
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So, when are we going to build Jurassic Park?

Author:  Müs [ Fri Dec 09, 2011 2:15 am ]
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Soon as we get the venture capital from Nevandal.

Author:  Lex Luthor [ Fri Dec 09, 2011 2:32 am ]
Post subject: 

Maybe Khross will let us construct it on his island.

Author:  Nevandal [ Fri Dec 09, 2011 3:44 am ]
Post subject:  Re:

Müs wrote:
Soon as we get the venture capital from Nevandal.



I would totally invest in this. :lol:

Author:  Elmarnieh [ Fri Dec 09, 2011 8:47 am ]
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That is going to be one weird population graph.

Author:  Lex Luthor [ Fri Dec 09, 2011 9:46 am ]
Post subject:  Re:

Elmarnieh wrote:
That is going to be one weird population graph.


Agreed. If humans weren't in the picture, you could explain it that a small group of mammoths were in hiding for 10,000 years. :D

Author:  Talya [ Fri Dec 09, 2011 10:03 am ]
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I want to have a mammoth burger washed down with one of these before I die.

Author:  Lex Luthor [ Fri Dec 09, 2011 10:10 am ]
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Cavemen couldn't help killing the rest of the mammoths off... they just wanted to make some more tasty burgers.

Author:  Stathol [ Fri Dec 09, 2011 12:16 pm ]
Post subject:  Re: Life... finds a way

This is certainly interesting. However, even if Dr. Wakayama's cloning technique proves fruitful for frozen mammoth specimens, I don't think anyone believes that it's possible to get an entire, un-damaged Mammoth genome out of any given sample. Or even necessarily from a combination of all known samples. I suspect that this (or something like this) will actually work, but that it will be necessary to "blend" the genome with some related organism -- probably elephants -- to make up for the missing pieces. The best-case scenario is probably something on the order of an 85/15 mammoth/elephant hybrid. That's ignoring the possibility that some of what we think is mammoth genome is not actually bacterial contamination.

Other random, disorganized thoughts:
  • How close are we to having a fully functional copy of a mammoth Y chromosome? This is a crucial "bottleneck" for obtaining a breeding pair of mammoths.
  • Elephants have 56 chromosomes, mammoths have 58. Theoretically, it might be possible to mate them and produce a (probably) infertile melemoth. For that matter, you might be able to at least temporarily solve the problem above by borrowing a Y chromosome from an elephant.
  • The divergence between elephant and mammoth DNA seems to be half that between humans and chimpanzees. To put that in perspective, the divergence between different (early and late) mammoth samples seems to be about 1/8th of the divergence between humans and chimpanzees.
  • Today I learned that you can buy DNA synthesizers for less than $1000 on eBay. Seriously. They're quite limited in the length of sequence you can produce (not even remotely close to synthesizing an entire chromosome), but still.

Author:  Talya [ Fri Dec 09, 2011 12:27 pm ]
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Okay...
So mammoth burgers then? With cheese or without?

Author:  Nevandal [ Fri Dec 09, 2011 1:00 pm ]
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Definitely with.

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